She was born Louisa Dupont Barker and her father ran a grocery store and pool hall, cashing in big time during prohibition with a stock of bootleg liquor. At 13 she left school and married Barker. , In 1930 the couple moved to New York, hooking up a variety of performing situations including the contact with Morton. At the 1938 Vocalion session at which she cut her first vocals, the producer checked her out and came up with the Blue Lu Barker stage name. The couple were contracted to Decca in the 30′s and the Apollo label the following decade, joining a roster at the latter label that included rhythm and blues and jazz greats such as Wynonie Harris, Dinah Washington and Luis Russell. One of the couple’s Apollo sessions even featured a jam with the mighty Charlie Parker. Blue Lu Barker was inducted into the Louisiana Blues Hall of Fame in 1997, one year before she died.